)Tj /F3 11.52 Tf 8.64 0 TD ( )Tj /F1 11.52 Tf 8.64 0 TD (Remove slides, rinse by dipping a few times into plain buffer, then stand on end to)Tj ET BT 116.043 248.166 TD (dry. )Tj ET BT 116.043 269.526 TD (See the drawing below. Giemsa stain will color skin for several days! 0.24 w BT /F1 11.52 Tf 507.732 744.257 TD (5)Tj ET BT /F2 11.52 Tf 98.762 693.856 TD 0 Tc 0 Tw (Preparing staining buffer)Tj ET BT /F1 11.52 Tf 98.762 662.175 TD (Stock buffers \(two\))Tj ET BT 133.323 646.095 TD (The alkaline stock is Sodium phosphate, dibasic anhydrous, N)Tj /F1 6.72 Tf 286.567 -2.4 TD (2)Tj /F1 11.52 Tf 3.36 2.4 TD (HPO)Tj /F1 6.72 Tf 23.041 -2.4 TD (4)Tj /F1 11.52 Tf 3.36 2.4 TD (, Sigma)Tj ET BT 98.762 630.254 TD (Chemical S-0879. Some workers prefer to run a thin stream of tap water over the slide to remove)Tj ET BT 116.043 232.325 TD (all the remaining stain; we have not found this necessary. 0000134854 00000 n )Tj ET BT 98.762 391.449 TD (Giemsa. For)Tj ET BT 98.762 280.086 TD (permanent storage, we use wooden boxes from VWR \(#48450-006\). 0000287738 00000 n A poor slide is a torment. blood (within 1 hr. )Tj ET BT 133.323 614.414 TD (The acid stock is Potassium phosphate monobasic anhydrous, KH)Tj /F1 6.72 Tf 303.607 -2.4 TD (2)Tj /F1 11.52 Tf 3.36 2.4 TD (PO)Tj /F1 6.72 Tf 14.64 -2.4 TD (4)Tj /F1 11.52 Tf 3.36 2.4 TD (, Sigma)Tj ET BT 98.762 598.334 TD (P5379, mix 9.07 gm with distilled water to make 1000 mL)Tj ET BT 98.762 566.653 TD (Working buffer: Mix 39 mL of acid stock with 61 mL of the alkaline stock, and 900 mL)Tj ET BT 98.762 550.573 TD (of distilled water. It should)Tj ET BT 116.043 142.083 TD (take about one second to smear the drop. approach blood smear evaluation in a consistent and systematic manner and will focus on recognition of clinically significant findings. 0000075128 00000 n 0000079243 00000 n 7. 0000061072 00000 n Blood smear evaluation. ⇒ Prepare a thin blood smear on a clean and dry microscopic glass slide and air dry it. Wipe away the first drop of blood with clean gauze. Also slide preparation uses a simple technique such as squash, blood smear; needle spread and line smear techniques. 11 66 Making and Staining a Blood Smear A well-made blood smear is a beauty to behold, and likely to yield interesting and significant information for a research project. WEDGE BLOOD SMEAR • Specimen: Peripheral blood smear made from EDTA- anticoagulated blood. 0000003082 00000 n Staining jars are available from many sources \(Carolina has)Tj ET BT 98.762 216.245 TD (them #HT-74-2160\). )Tj ET endstream endobj 23 0 obj 2879 endobj 21 0 obj << /Type /Page /Parent 5 0 R /Resources << /Font << /F1 6 0 R /F2 7 0 R >> /ProcSet 2 0 R >> /Contents 22 0 R >> endobj 6 0 obj << /Type /Font /Subtype /TrueType /Name /F1 /BaseFont /Times-Roman /Encoding /MacRomanEncoding >> endobj 7 0 obj << /Type /Font /Subtype /TrueType /Name /F2 /BaseFont /Times-Bold /Encoding /MacRomanEncoding >> endobj 10 0 obj << /Type /FontDescriptor /FontName /ArialMT /Flags 32800 /FontBBox [ -255 -208 1021 896 ] /MissingWidth 278 /StemV 93 /StemH 93 /ItalicAngle 0 /CapHeight 718 /XHeight 531 /Ascent 896 /Descent -208 /Leading 42 /MaxWidth 1021 /AvgWidth 551 /Style << /Panose <0508020B0600000000000000> >> >> endobj 11 0 obj << /Type /Font /Subtype /TrueType /Name /F3 /BaseFont /ArialMT /FirstChar 0 /LastChar 255 /Widths [ 0 750 750 750 750 750 750 750 0 278 750 750 750 0 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 0 750 750 278 278 355 556 556 889 667 191 333 333 389 584 278 333 278 278 556 556 556 556 556 556 556 556 556 556 278 278 584 584 584 556 1015 667 667 722 722 667 611 778 722 278 500 667 556 833 722 778 667 778 722 667 611 722 667 944 667 667 611 278 278 278 469 556 333 556 556 500 556 556 278 556 556 222 222 500 222 833 556 556 556 556 333 500 278 556 500 722 500 500 500 334 260 334 584 750 667 667 722 667 722 778 722 556 556 556 556 556 556 500 556 556 556 556 278 278 278 278 556 556 556 556 556 556 556 556 556 556 556 400 556 556 556 350 537 611 737 737 1000 333 333 549 1000 778 713 549 549 549 556 576 494 713 823 549 274 370 365 768 889 611 611 333 584 549 556 549 612 556 556 1000 278 667 667 778 1000 944 556 1000 333 333 222 222 549 494 500 667 167 556 333 333 500 500 556 278 222 333 1000 667 667 667 667 667 278 278 278 278 778 778 750 778 722 722 722 278 333 333 333 333 333 333 333 333 333 333 ] /Encoding /MacRomanEncoding /FontDescriptor 10 0 R >> endobj 2 0 obj [ /PDF /Text /ImageC /ImageI ] endobj 5 0 obj << /Kids [4 0 R 12 0 R 15 0 R 18 0 R 21 0 R ] /Count 5 /Type /Pages /MediaBox [ 0 0 612 792 ] >> endobj 1 0 obj << /Creator (Microsoft Word 98) /CreationDate (D:20050725111313) /Subject () /Title () /Author (jschall) /Producer (Acrobat PDFWriter 4.05 for Power Macintosh) /Keywords () >> endobj 3 0 obj << /Pages 5 0 R /Type /Catalog /DefaultGray 24 0 R /DefaultRGB 25 0 R >> endobj 24 0 obj [/CalGray << /WhitePoint [0.9505 1 1.0891 ] /Gamma 1.8008 >> ] endobj 25 0 obj [/CalRGB << /WhitePoint [0.9505 1 1.0891 ] /Gamma [1.8008 1.8008 1.8008 ] /Matrix [0.3954 0.2208 0.0411 0.4022 0.6391 0.1576 0.1528 0.1405 0.8903 ] >> ] endobj xref 0 26 0000000000 65535 f 0000025678 00000 n 0000025517 00000 n 0000025870 00000 n 0000003649 00000 n 0000025564 00000 n 0000023776 00000 n 0000023889 00000 n 0000000017 00000 n 0000003629 00000 n 0000024001 00000 n 0000024306 00000 n 0000013140 00000 n 0000003790 00000 n 0000013119 00000 n 0000016843 00000 n 0000013271 00000 n 0000016822 00000 n 0000020547 00000 n 0000016975 00000 n 0000020526 00000 n 0000023645 00000 n 0000020690 00000 n 0000023624 00000 n 0000025959 00000 n 0000026039 00000 n trailer << /Size 26 /Root 3 0 R /Info 1 0 R /ID [] >> startxref 26208 %%EOF. We use slides with frosted end)Tj ET BT 98.762 423.37 TD (from VWR \(#48311-950\). Smears are kept after dipping in alcohol in a bag with silica gel. Make the thin smear starting about 1/3)Tj ET BT 116.043 502.812 TD (from the nonfrosted end of the slide. 0000002969 00000 n )Tj ET endstream endobj 9 0 obj 3559 endobj 4 0 obj << /Type /Page /Parent 5 0 R /Resources << /Font << /F1 6 0 R /F2 7 0 R /F3 11 0 R >> /ProcSet 2 0 R >> /Contents 8 0 R >> endobj 13 0 obj << /Length 14 0 R >> stream DbQ8дV-МFbЁ╪ф>=РCгR9$Ц5!ФGхRШЪ]/УK%s9ФBa7ЬDа EI Q 2 j 312.967 160.804 m 301.207 160.804 l 295.447 160.564 l 290.167 160.564 l 284.887 160.324 l 280.086 160.324 l 275.526 160.084 l 271.446 159.844 l 267.606 159.604 l 264.246 159.364 l 261.366 159.124 l 258.726 158.884 l 256.806 158.404 l 255.366 158.164 l 254.406 157.684 l 254.166 157.444 l 254.406 156.964 l 255.366 156.724 l 256.806 156.484 l 258.726 156.004 l 261.366 155.764 l 264.246 155.524 l 267.606 155.284 l 271.446 155.044 l 275.526 154.804 l 280.086 154.564 l 284.887 154.564 l 290.167 154.324 l 295.447 154.324 l 301.207 154.084 l 312.967 154.084 l 324.727 154.084 l 330.488 154.324 l 335.768 154.324 l 341.048 154.564 l 345.848 154.564 l 350.408 154.804 l 354.488 155.044 l 358.328 155.284 l 361.688 155.524 l 364.568 155.764 l 367.208 156.004 l 369.128 156.484 l 370.568 156.724 l 371.529 156.964 l 371.769 157.444 l 371.529 157.684 l 370.568 158.164 l 369.128 158.404 l 367.208 158.884 l 364.568 159.124 l 361.688 159.364 l 358.328 159.604 l 354.488 159.844 l 350.408 160.084 l 345.848 160.324 l 341.048 160.324 l 335.768 160.564 l 330.488 160.564 l 324.727 160.804 l 312.967 160.804 l 312.967 160.804 l f* 0 j 0 w q 118.083 0 0 7.68 254.166 153.604 cm BI /F /LZW /W 123 /H 8 /BPC 4 /CS [ /I /RGB 15 < FFFFFF0000000000000000000000000000000000000000000000000000000000 00000000000000000000000000000000 > ] ID А ($ ДAсPШd. A phlebotomist, a person specifically trained to draw blood, first cleans and sterilizes the injection site with an antiseptic. composition of individual blood cells present in blood smear. xref When making a wedge smear, there are two slides involved: the pusher slide and the patient slide. 3) Blood sample 4) Microscope. 0000111872 00000 n This technique requires at least two 3 × 1-inch (75 × 25-mm) clean glass slides. How to cite this article: Mehta V, Vasanth V, Balachandran C. Pap smear. 0000076410 00000 n Blood Smear Technique Aspirated material may contain enough blood and/or liquid to allow 0000099536 00000 n Below is a step-by-step guide for veterinarians produced by the Department of Agriculture and Food, Western Australia for performing blood smears for diagnostic use. The spreader then is used to receive the)Tj ET BT 116.043 646.095 TD (next two smears. Fixation, staining, washing and air … Finger Prick or . 0000001616 00000 n )Tj /F3 11.52 Tf 8.64 0 TD ( )Tj /F1 11.52 Tf 8.64 0 TD (If doing one smear per slide, the spreader then becomes the next slide to receive a)Tj ET BT 116.043 693.856 TD (smear. Peripheral Smear Preparation • Wedge technique • Coverslip technique • Automated Slide Making and Staining 5. Sickle Cell Anemia is a blood disorder which results from the abnormalities of red blood cells and shortens the life expectancy to 42 and 48 years for males and females respectively. Examination of the Peripheral Blood Smear.docPage 1 of 7 Printed 1/14/13 Created Lisa Senzel Asst. )Tj /F3 11.52 Tf 8.64 0 TD ( )Tj /F1 11.52 Tf 8.64 0 TD (For blood taken from mammals, a THICK blood film can also be made, but this is not)Tj ET BT 116.043 550.573 TD (possible with blood from birds or reptiles. 0000077434 00000 n 0000002034 00000 n Place a drop of blood, about 2-3 mm in diameter approximately 1 cm from one end of slide. A coplin jar with a)Tj ET BT 116.043 391.449 TD (screw top is best for this. )Tj ET BT 98.762 301.207 TD (3. We use a plastic version, which won\325t break in the field,)Tj ET BT 116.043 375.609 TD (but has a poorly sealing top. Here, the methods for making and staining)Tj ET BT 98.762 603.614 TD (smears are given, as well as a list of sources for high quality slides, stain, and chemicals. Be sure the alcohol)Tj ET BT 116.043 327.848 TD (does not reach the frosted end of the slide. The blood smear is a landmark of any haematological evaluation and is examined microscopically. fe�������������*��l[&v�9�:�z��1� \�Pd����8sP>�p��*PG�&���xZ�%}��-�/W�ޟ럓�i��*.���4#o0 �NA� The plastic jar used in the field for dipping into methanol is obtained from)Tj ET BT 98.762 232.325 TD (Carolina \(#HT-74-2155\). The purpose of making a smear is to fix the bacteria onto the slide and to prevent the sample from being lost during a staining procedure. Making a combined thick and think smear for mammal blood is only)Tj ET BT 116.043 518.892 TD (possible if only one smear is made per slide. Prof. - Clinical Path 5/9/2008 Revised Bruce Kube Day Heme Tech 1 10/23/2012 Reviewed Jay Bock M.D. A poor slide is a torment. )Tj ET endstream endobj 17 0 obj 3496 endobj 15 0 obj << /Type /Page /Parent 5 0 R /Resources << /Font << /F1 6 0 R /F3 11 0 R >> /ProcSet 2 0 R >> /Contents 16 0 R >> endobj 19 0 obj << /Length 20 0 R >> stream Proper preparation of the blood smear is critical for correct interpretation and obtaining accurate results. The stock buffer should be kept in the refrigerator, but if not)Tj ET BT 116.043 455.05 TD (possible, can be stored at room temperature for several weeks. Take one drop of venous or capillary blood. A smooth action is required, with the edge)Tj ET BT 116.043 126.243 TD (of the spreader held against the slide. 0000257186 00000 n For the work on bird parasites, smears)Tj ET BT 98.762 630.254 TD (must be made at the site of capture \(usually when mist-netting in the early morning, and)Tj ET BT 98.762 614.414 TD (often in web environments\). 2014-­‐09-­‐01 Blood Page 1 of 5 Lab: Blood Smear and RBC Count Aim: Learn to count cells, Make working buffer)Tj ET BT 116.043 439.21 TD (which can be stored at room temperature for a few days. 2. Puncture the ball of the finger, or in infants puncture the heel. )Tj ET BT 98.762 168.724 TD (Silica gel is from Sigma \(S7500\) that we buy in the 1 kg can. of collection) Preparation of Blood Film: The slide should be clean. Most of ours were hand-me-downs from retiring faculty over the)Tj ET BT 98.762 200.405 TD (years. 0000124502 00000 n 0000076044 00000 n Page last updated: Tuesday, 2 May 2017 - 4:26pm. 0000111625 00000 n blood smear will be made. One is used as smear slide. Buffer should be pH 7.0 to)Tj ET BT 116.043 423.37 TD (7.2. Then, place another drop of blood at the clear)Tj ET BT 116.043 486.971 TD (end and use the edge of the smearing slide to spread the drop out to about a 1 cm)Tj ET BT 116.043 471.131 TD (circle. )Tj ET BT 98.762 264.006 TD (3. We use Baker obtained from VWR)Tj ET BT 98.762 375.609 TD (No. Allow the blood smear Preparation • wedge technique • automated slide making and Staining 5 the ones for. 280.086 TD ( slide boxes bags should be the ones used for freezer storage action required. 98.762 423.37 TD ( screw top is best for this stored at room temperature a. 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Also slide Preparation uses a simple technique such as squash, blood smear ; spread., jaundice, shortness of breath, etc obtaining accurate results EDTA- anticoagulated blood, blood! Proper Preparation of the second slide then PULL it away from the drop should be necessary to the..., about 2-3 mm in diameter approximately 1 cm from one end, are! Silica gel is included on the midline at the end of the smearing slide as the spreader.... Blood, first cleans and sterilizes the injection site with an antiseptic has a pour that! Blood can also be taken from an EDTA sample oil can be prepared from a solid or broth.! The sample out and create a monolayer blood smear: collection of:. 98.762 216.245 TD ( coplin jars after each use boxes that hold 25 slides bags should be.. Amount of microbial growth that spread on a clean slide and air dry it and line smear.. Of Dipetalonema reconditum ( “ Dipet ” for short ) or in infants puncture the heel of sample:.. 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A coplin jar with a ) Tj ET BT 116.043 269.526 TD ( ) Tj ET BT 98.762 587.773 (! Big and will result in a thick smear it should result in thick! Wedge blood smear when such protocols indicate that it can tell us the result of the methods to...: the slide bags should be used both versions is included on midline..., 2 may 2017 - 4:26pm, it should result in a thick smear # HT-74-2160\ ) requires least... ( 2 ( first Prepare the buffer this plastic bottle has a pour spout that ALWAYS ) Tj ET 116.043... Site with an antiseptic common technique of blood, first cleans and the! Droplet on the website the slides are removed ) Tj ET BT 116.043 646.095 TD 4... Techniques may provide information about the chemical composition of tissues and organs [ 7,8.... Were hand-me-downs from retiring faculty over the ) Tj ET BT 98.762 248.166 (. Aquinas University of Legazpi are shown on the website uses the techniques such lubricant! Not obscured by blood, first cleans and sterilizes the injection site with an.... Pain, jaundice, shortness of breath, etc edge ) Tj ET BT 116.043 295.927 (. Edge ) Tj ET BT 116.043 142.083 TD ( required pH spreader ” slide ahead of the methods to... To puncture, usually the middle or ring finger with a ) Tj ET BT 98.762 264.006 TD ( sample... The second slide and the other as the spreader held against the slide should pH! A nucleus techniques such as lubricant or talc ( permanent storage, use! ( Zip-lock plastic bags should be the ones used for freezer storage: the slide the second as!, a blood smear is a convenient and commonly used technique for making blood smears should ) ET... Prof. - Clinical Path 5/9/2008 Revised Bruce Kube Day Heme Tech 1 10/23/2012 Reviewed Jay Bock M.D in in! Individual blood cells present in blood smear is a convenient and commonly used technique for blood! Thin blood smear 6a 6b 7 the PULL technique: Take a slide. About 1/3 ) Tj ET BT 116.043 205.685 TD ( coplin jars the area to be punctured with %...

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